Comparison of Antimicrobial Properties of Monoterpenes and their Carbonylated Products
Ruth Naigre, Philippe Kalck, Christine Roques, Isabelle Roux, G. Michel
Planta Medica
Abstract
Some monoterpenes and their carbonylated products were evaluated for their antibacterial and antifungal properties. The carbonylation of tested monoterpenes was shown to increase the bacteriostatic and fungistatic activities specifically by the contact method. Concerning the killing effects, only (1R,2S,5R)-isopulegol, its carbonylated products, and (R)-carvone showed significant bactericidal activities, particularly against Enterococcus faecium and Escherichia coli above a concentration of 10 microliters/ml. A fungicidal efficiency of (1R,2S,5R)-isopulegol and (R)-carvone against Aspergillus niger was also noted. It seems that the presence of an oxygenated function in the framework increases the antimicrobial properties. However, monoterpenes were more active using a micro-atmosphere method.
Extracted Claims
5 claims extracted from this paper into the knowledge graph
(R)-carvone showed significant bactericidal activities against Enterococcus faecium and Escherichia coli
“Only (1R,2S,5R)-isopulegol, its carbonylated products, and (R)-carvone showed significant bactericidal activities, particularly against Enterococcus faecium and Escherichia coli above a concentration ...”
(R)-carvone showed fungicidal efficiency against Aspergillus niger
“A fungicidal efficiency of (1R,2S,5R)-isopulegol and (R)-carvone against Aspergillus niger was also noted.”
(1R,2S,5R)-isopulegol showed fungicidal efficiency against Aspergillus niger
“A fungicidal efficiency of (1R,2S,5R)-isopulegol and (R)-carvone against Aspergillus niger was also noted.”