2022peer-reviewed61 citations
Evaluating Vitamin C in Septic Shock: A Randomized Controlled Trial of Vitamin C Monotherapy*
David A. Wacker, Susan L. Burton, John P. Berger, A. J. Hegg, Jamie Heisdorffer, Qi Wang +2 more
Critical Care Medicine
Abstract
Vitamin C monotherapy failed to significantly reduce mortality in septic shock patients as hypothesized. Our findings do not support its routine clinical use for this purpose.
Concepts
MedicineVitamin CSeptic shockRandomized controlled trialInternal medicineGastroenterologyAscorbic acidShock (circulatory)