Utilization Efficiency of Human Milk Oligosaccharides by Human-Associated <i>Akkermansia</i> Is Strain Dependent
Estefani Luna, Shanthi G. Parkar, Nina Kirmiz, Stephanie Hartel, Erik Hearn, Marziiah Hossine +13 more
Applied and Environmental Microbiology
Abstract
Human milk oligosaccharides (HMOs) are the third most abundant component of breast milk and provide several benefits to developing infants, including the recruitment of beneficial bacteria to the human gut. Akkermansia strains are largely considered beneficial bacteria and have been detected in colostrum, breast milk, and young infants. A. muciniphila Muc T belonging to the AmI phylogroup contributes to the HMO deconstruction capacity of the infant. Here, using phylogenomics, we examined the genomic capacities of four Akkermansia phylogroups to deconstruct HMOs.
Extracted Claims
1 claim extracted from this paper into the knowledge graph
Human milk oligosaccharides (HMOs) contribute to HMO deconstruction capacity of the infant
“A. muciniphila Muc T belonging to the AmI phylogroup contributes to the HMO deconstruction capacity of the infant.”