Cuproptosis: Mechanisms, biological significance, and advances in disease treatment—A systematic review
Chengliang Pan, Zhilin Ji, Qingxuan Wang, Zhao Zhang, Zhenchuan Wang, Chen Li +2 more
CNS Neuroscience & Therapeutics
Abstract
The study highlights the need for further research to explore alternative pathways of copper-induced cell death, detailed mechanisms of cuproptosis, and biomarkers for copper poisoning. Future research should focus on exploring the molecular mechanisms of cuproptosis, developing new therapeutic strategies, and verifying their safety and efficacy in clinical trials.