Independent Risk Factors for Atrial Fibrillation in a Population-Based Cohort

Abstract

<h3>Objective.</h3> —To determine the independent risk factors for atrial fibrillation. <h3>Design.</h3> —Cohort study. <h3>Setting.</h3> —The Framingham Heart Study. <h3>Subjects.</h3> —A total of 2090 men and 2641 women members of the original cohort, free of a history of atrial fibrillation, between the ages of 55 and 94 years. <h3>Main Outcome Measures.</h3> —Sex-specific multiple logistic regression models to identify independent risk factors for atrial fibrillation, including age, smoking, diabetes, electrocardiographic left ventricular hypertrophy, hypertension, myocardial infarction, congestive heart failure, and valve disease. <h3>Results.</h3> —During up to 38 years of follow-up, 264 men and 298 women developed atrial fibrillation. After adjusting for age and other risk factors f