Saccharomyces boulardii → is safe and efficacious → prevention of antibiotic-associated diarrhea (AAD)
population: adultsstudy_type: randomized, blinded controlled trials
“A meta-analysis found a significant therapeutic efficacy for S. boulardii in the prevention of antibiotic-associated diarrhea (AAD) (RR = 0.47, 95% CI: 0.35-0.63, P < 0.001).”
Saccharomyces boulardii → is safe and efficacious → prevention of enteral nutrition-related diarrhea
population: adultsstudy_type: randomized, blinded controlled trials
“Randomized trials also support the use of this yeast probiotic for prevention of enteral nutrition-related diarrhea.”
Saccharomyces boulardii → is safe and efficacious → prevention of traveler's diarrhea
population: adultsstudy_type: randomized, blinded controlled trials
“In adults, S. boulardii can be strongly recommended for the prevention of AAD and the traveler's diarrhea.”
Saccharomyces boulardii → is safe and efficacious → reduction of Helicobacter pylori treatment-related symptoms
population: adultsstudy_type: randomized, blinded controlled trials
“Randomized trials also support the use of this yeast probiotic for reduction of Helicobacter pylori treatment-related symptoms.”
Saccharomyces boulardii CNCM I-745 → had no → adverse effects
dose: 50mg/kgfrequency: twice a daypopulation: preterm infants >30 weeks old
“Prophylactic supplementation of S. boulardii at a dose of 50mg/kg twice a day improved weight gain, improved feeding tolerance, and had no adverse effects in preterm infants >30 weeks old.”
Saccharomyces boulardii → is safe and well-tolerated → treatment of diarrhea
“Recent studies have confirmed that S. boulardii is effective in the treatment of diarrhea, in particular chronic or recurrent diarrhea, and furthermore that it is a safe and well-tolerated treatment.”
Saccharomyces boulardii → causes → fungaemia
context: critically ill patients
“As the prescription of probiotic containing S. boulardii in critically ill patient's leads to the fungaemia, we recommend avoiding this probiotic in those patients.”
